ABSTRACT: Radiolarians of the order Latentifistularia are described from strata of the Roadian Stage (Guadalupian Series, middle Permian) exposed in a small roadside quarry (Quarry section) in the Guadalupe Mountains, West Texas. The families Cornellidae Kozur and Mostler and Ishigaidae Kozur and Mostler are discussed. The genus Pseudotormentus is reassigned to the family Latentifistulidae. The genus Octatormentum and species Latentifistula patagilaterala, Quinqueremis robusta, Ormistonella minima, Tetratormentum nitidus and Octatormentum cornelli are revised. The species Tormentum delicatum assigned to the genus Rectotormentum. One genus, Nabespecha, is reinstated herein. Three new genera, Murcheyella, Sashitonishella and Quadrulites, and 17 new species: Latentifistula crassa, L. macilenta, L. coniformis, Murcheyella marginata, Latentibifistula dellensis, Pseudotormentus ornatus, Cauletella caridroiti, Praedeflandrella insueta, Quinqueremis pentagonus, Q. porosus, Sashitonishella rara, Polyfistula composita, Ormistonella aetheria, O. decurvata, Tetragregnon delawarus, Tormentum lobatum, and Grandetortura sashidai are described.